New Advances in Chemical Research in 2021, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 104-66-5, Name is 1,2-Diphenoxyethane, molecular formula is C14H14O2, belongs to isothiazole compound. In a document, author is Ciez, Dariusz, introduce the new discover, Name: 1,2-Diphenoxyethane.
An oxidative dimerization of titanium(IV) enolates derived from menthyl esters of 2-isothiocarboxylic acids leads to radical coupling followed by cyclization. This cascade reaction gives thiazolo[5,4-d]thiazole derivatives as pure enantiomers. Under similar conditions, 2-methylbutyl esters of 2-isothiocyanatocarboxylic acids undergo intermolecular oxidative dimerization to give mixtures of thiazolo[5,4-d]thiazoles and 2,3-diisothiocyanatosuccinates. Application of the soft enolization technique to dimethyl alpha,alpha’-diisothiocyanatodicarboxylic esters gives novel cyclic 1,2-diisothiocyanato-1,2-dicarboxylates. Sodium enolates of 2-isothiocyanatocarboxylates, on the other hand, form 5-imino-2-thioxo-1,3-thiazolidine-4-carboxylic esters by nonoxidative dimerization. The mechanisms of the two reaction pathways are discussed.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 104-66-5. Name: 1,2-Diphenoxyethane.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com