New discoveries in chemical research and development in 2021, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 3218-36-8, Name is [1,1′-Biphenyl]-4-carbaldehyde, SMILES is O=CC1=CC=C(C2=CC=CC=C2)C=C1, in an article , author is Kalogirou, Andreas S., once mentioned of 3218-36-8, Formula: C13H10O.
Ring transformation of readily prepared (4-chloro-5H-1,2,3-dithiazol-5-ylidene)acetonitriles afford 3-haloisothiazole-5-carbonitriles in good to excellent yields. The transformation can be mediated using HBr (g), HCl (g) or BnEt3NCl. Mechanisms for the transformations are discussed, together with rationalizations for the formation of side products. Furthermore, single crystal X-ray structures are provided for (Z)-2-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)acetonitrile and (E)-2-bromo-2-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)acetonitrile confirming the stereochemistry of the exocyclic ethene bond.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield. If you are hungry for even more, make sure to check my other article about 3218-36-8, Formula: C13H10O.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com