A common heterocyclic compound, the isothiazole compound, name is 3-Piperazinobenzisothiazole hydrochloride,cas is 87691-88-1, mainly used in chemical industry, its synthesis route is as follows.,87691-88-1
The above intermediate IV (0.01 mol) and the hydrochloride salt of the piperazine compound (V) (0.01 mol)Dissolved in DMF (100 mL) and added K2CO3 (0.02 mol).According to the general operation three,Preparation of 3-(4-(2-(5-fluoro-1H-indol-3-yl)ethyl)piperazin-1-yl)benzo[d]isothiazole (VI-1)Hydrochloride (white solid) 2.5 g, yield 60%.
As the rapid development of chemical substances, we look forward to future research findings about 87691-88-1
Reference£º
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Gu Zhengsong; Zhou Ainan; Xiao Ying; (26 pag.)CN109467554; (2019); A;,
Isothiazole – Wikipedia
Isothiazole – ScienceDirect.com