New research progress on 2051-95-8 in 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 2051-95-8, Name is 3-Benzoylpropionicacid, formurla is C10H10O3. In a document, author is Soni, Sonam, introducing its new discovery. Category: isothiazole.
An operationally simple and user-friendly process to access privileged scaffolds such as acids, amides and isothiazoles has been devised employing beta-ketodithioesters for the first time. Remarkably, the new protocol involves combination of C-C bond cleavage and C-O/C N/N-S bond formations in one-pot. Aqueous ammonia led to the formation of skeletally distinct amide and isothiazole, whereas aqueous NaOH enabled the formation of aromatic acid near quantitative yield. This practical approach, which can dramatically streamline the synthesis of simple molecules, is highly chemoselective, cost-effective, amenable to gram scale, insensitive to moisture as well as bears high functional group compatibility. (C) 2017 Elsevier Ltd. All rights reserved.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. Interested yet? Keep reading other articles of 2051-95-8, you can contact me at any time and look forward to more communication. Category: isothiazole.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com