In an article, author is CLERICI, F, once mentioned the application of 564-25-0, Name is (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, molecular formula is C22H24N2O8, molecular weight is 444.4346, MDL number is MFCD00800994, category is isothiazole. Now introduce a scientific discovery about this category, Recommanded Product: 564-25-0.
N-SULFONYLAMIDINES .4. INTRAMOLECULAR CYCLIZATION OF N-SULFONYLAMIDINES OF 2-OXOACIDS – A NEW SYNTHESIS OF 3-AMINOISOTHIAZOLE S,S-DIOXIDES
N-alkylsulfonylamidines of alpha-ketoacids 3 bearing both a carbonyl group and at least one H-atom near to the SO2 group give easily an intramolecular ring-closure reaction by action of potassium t-butoxide producing the 3-amino-4,5-dihydro-4-hydroxy-isothiazole S,S-dioxides 4. Compounds 4 are transformed by thionyl chloride into the corresponding chloro-derivatives 5 which in turn are dehydrochlorinated by potassium carbonate to substituted 3-amino-isothiazole S,S-dioxides 6.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com