Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 503-29-7, Name is Azetidine, molecular formula is C3H7N. In an article, author is Vicini, Paola,once mentioned of 503-29-7, Formula: C3H7N.
Anti-HIV evaluation of benzo[d]isothiazole hydrazones
The synthesis and the anti-HIV-1 activity of novel benzo[d]isothiazole hydrazones are reported. Target compounds tested in MT-4 cells cultures for their anti-HIV properties against wild type HIV-1 and HIV strains carrying clinically relevant mutations (EFV(R), Y181C and K103/Y181C) showed good activity against wild type HIV-1 and against the EFVR mutant. In terms of SAR the relevant result was that, in the class of benzisothiazole hydrazones, the benzo[d]isothiazol-3(2H)-one moiety (compounds 1 and 4) is an essential structural requirement for the anti-retroviral activity. (C) 2008 Elsevier Masson SAS. All rights reserved.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com