Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 2051-95-8, Name is 3-Benzoylpropionicacid, molecular formula is C10H10O3. In an article, author is LASNE, MC,once mentioned of 2051-95-8, Product Details of 2051-95-8.
PREPARATION OF [F-18] RP-62203, A SELECTIVE LIGAND FOR THE STUDY OF SEROTONIN RECEPTORS (5-HT2) BY RAPID IN-SITU PIPERAZINE FORMATION
2-[3-(4-(4[F-18]Fluorophenyl)-1-piperazinyl)propyl]-2H-naphth[1,8-cd]isothiazole-1,1-dioxide] ([F-18]RP 62203), an antagonist of 5-HT2 receptors, was prepared from [F-18]fluoride via a 3-step reaction sequence, with an overall radiochemical yield of 5-12% (decay corrected) and within 190-230 min (total automated synthesis from EOB). The key step involved the rapid (6 min, 150 degrees C in octanol) and efficient (> 65%) reaction of an appropriate bis(bromoethyl)amine derivative with 4-[F-18]fluoroaniline.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com