A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Product Details of 35285-69-9, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 35285-69-9, Name is Sodium 4-(propoxycarbonyl)phenolate, molecular formula is C10H11NaO3. In an article, author is Lippa, B,once mentioned of 35285-69-9.
Discovery of novel isothiazole inhibitors of the TrkA kinase: Structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists
The design, synthesis, and biological evaluation of potent inhibitors of the TrkA kinase is presented. A homology model is created to aid in the enhancement of potency and selectivity of isothiazole inhibitors found during a high-throughput screen. Three different syntheses are utilized to make diverse analogs within this series. Aminoheterocycles are found to be good urea surrogates, whereas bicyclic substituents on the C3 thio group were found to be extremely potent TrkA inhibitors in kinase and cell assays. (c) 2006 Elsevier Ltd. All rights reserved.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com