New ligands with a wide bite angle. Efficient catalytic activity in the Rh(I)-catalyzed hydroformylation of olefins was written by Yamamoto, Keiji;Momose, Satoru;Funahashi, Masakazu;Ebata, Satoshi;Ohmura, Hideaki;Komatsu, Hiroshi;Miyazawa, Masahiro. And the article was included in Chemistry Letters in 1994.Recommanded Product: 1-((3aS,6R,7aR)-8,8-Dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)prop-2-en-1-one This article mentions the following:
The relevance of a new diphosphinite (I), which holds a natural bite angle around 120° in a catalyst complex, to the Rh(I)-catalyzed hydroformylation of certain olefins is examined, exhibiting a high turnover frequency (TOF) as compared with a typical 1,2-bis(diphenylphosphino)ethane with a bite angle around 85°. In the experiment, the researchers used many compounds, for example, 1-((3aS,6R,7aR)-8,8-Dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)prop-2-en-1-one (cas: 94594-91-9Recommanded Product: 1-((3aS,6R,7aR)-8,8-Dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)prop-2-en-1-one).
1-((3aS,6R,7aR)-8,8-Dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)prop-2-en-1-one (cas: 94594-91-9) belongs to isothiazole derivatives. Isothiazoles and isothiazolium cations are attacked by carbanions at sulfur and on recyclization can give thiophenes. Many compounds with an isothiazole scaffold demonstrated a wide range of biological profiles, including antiinflammatory, antithrombotic, and anticonvulsive agents.Recommanded Product: 1-((3aS,6R,7aR)-8,8-Dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)prop-2-en-1-one
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com