Catalytic enantioselective synthesis of 3-substituted benzosultams via Corey-Bakshi-Shibata reduction of cyclic N-sulfonylimines was written by Enders, Dieter;Seppelt, Matthias. And the article was included in Synlett in 2011.Product Details of 62473-92-1 This article mentions the following:
The catalytic asym. synthesis of 3-substituted benzo-fused sultams I (R1 = Me, Et, n-Bu, Ph; R2 = H, Br) in good to excellent yields of 74-95% and enantiomeric excesses of 69-94% by the Corey-Bakshi-Shibata reduction of the corresponding cyclic N-sulfonylimines with catecholborane is reported. In the experiment, the researchers used many compounds, for example, 6-Bromobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 62473-92-1Product Details of 62473-92-1).
6-Bromobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 62473-92-1) belongs to isothiazole derivatives. Isothiazoles and their saturated and/or oxygenated analogs play an important role in pharmaceutical research. Many compounds with an isothiazole scaffold demonstrated a wide range of biological profiles. Some of these molecules have been efficiently used in the treatment of Alzheimer’s disease.Product Details of 62473-92-1
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com