Nederlof, A.’s team published research in Recueil des Travaux Chimiques des Pays-Bas in 81 | CAS: 7668-28-2

Recueil des Travaux Chimiques des Pays-Bas published new progress about 7668-28-2. 7668-28-2 belongs to isothiazole, auxiliary class Sulfamide,Amine,Benzothiazole, name is 3-Aminobenzo[d]isothiazole 1,1-dioxide, and the molecular formula is C7H6N2O2S, Product Details of C7H6N2O2S.

Nederlof, A. published the artcileChemistry of rhodanine and its derivatives. Preliminary communication, Product Details of C7H6N2O2S, the publication is Recueil des Travaux Chimiques des Pays-Bas (1962), 578-80, database is CAplus.

Impure 5-(2,4-dinitrobenzylidne)-3-ethylrhodanine, m. 133°, was prepared by condensing 3-ethylrhodanine with 2,4-dinitrobenzaldehyde. Refluxing the impure product with EtOAc gave the more pure compound and presumably I (R = Et), m. 252-2.5°. The addition of large quantities of p-MeC6H4SO2Cl accelerated the formation of orange I (R = Et), as well as of I (R = CH2CH:CH2), m. 190.5-1°, and I (R = CH2CO2Et), m. 183-4°. These compounds reduced to readily autoxidized II (R = Et), light yellow, m. 155-7°, II (R = CH2CH:CH2), yellow, m. 121.5-3.5°, and II (R = CH2CO2Et), nearly colorless, m. 169-70°, resp. The “anil method” of rhodanine condensation gave purer compounds with higher yields. 3-Aminorhodanine reacted in boiling EtOH with p-nitrobenzaldehyde to give orange 3-amino-5-(p-nitrobenzylidene)rhodanine, m. 230-1°, not the yellow 3-(p-nitrobenzylidenamino)rhodanine as reported by Ueda and Ohta (CA 52, 401d).

Recueil des Travaux Chimiques des Pays-Bas published new progress about 7668-28-2. 7668-28-2 belongs to isothiazole, auxiliary class Sulfamide,Amine,Benzothiazole, name is 3-Aminobenzo[d]isothiazole 1,1-dioxide, and the molecular formula is C7H6N2O2S, Product Details of C7H6N2O2S.

Referemce:
https://en.wikipedia.org/wiki/Isothiazole,
Isothiazole – ScienceDirect.com