Inagaki, Masanao published the artcileShort Synthesis of tert-Butyl-Hydroxylated 3,5-Di-tert-butyl-4-hydroxybenzaldehyde: Synthesis of tert-Butyl-Hydroxylated S-2474, Formula: C5H11NO2S, the main research area is hydroxybenzaldehyde hydroxybutyl preparation; oxidizing agent hydrobromic acid DMSO; antiarthritic drug S2474 metabolite preparation.
We have developed a very short synthesis of tert-butyl-hydroxylated di-tert-butyl-4-hydroxybenzaldehyde (I) in which the HBr-DMSO system is used as an effective oxidant (overall yield of 45% for the entire four-step process from 2-tert-butyl-p-cresol). We also accomplished the synthesis of a major metabolite (II) of the antiarthritic drug candidate S-2474.
Journal of Organic Chemistry published new progress about Oxidizing agents (hydrobromic acid-DMSO). 73343-04-1 belongs to class isothiazole, name is 2-Ethylisothiazolidine 1,1-dioxide, and the molecular formula is C5H11NO2S, Formula: C5H11NO2S.
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com