On March 31, 1995, Suzuki, Tetsuya published a patent.Safety of 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Photographic emulsions containing isothiazolin-3-ones. And the patent contained the following:
Photog. emulsions are prepared by addition of isothiazolin-3-ones I (R1 = H, alkyl, cycloalkyl, alkenyl, alkoxy, aryl, heterocycle, CONH2, etc.; R2-3 = H, halo, alkyl,, cycloalkyl, aryl, cyano, alkylthio, etc.; R2 and R3 may form a benzene ring) during the period from nucleation of emulsion grains to the termination of chem. ripening. The photog. materials show little dependence on humidity and little change in sensitivity from the time lapse from exposure to processing. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Safety of 2-Methylisothiazol-3(2H)-one hydrochloride
The Article related to emulsion photog isothiazolinone stabilizer, Radiation Chemistry, Photochemistry, and Photographic and Other Reprographic Processes: Silver Halide Photographic Chemistry and Processes and other aspects.Safety of 2-Methylisothiazol-3(2H)-one hydrochloride
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com