Mine, Kyomitsu et al. published their patent in 1984 |CAS: 26172-54-3

The Article related to antiseptic treatment photog emulsion, phenol photog emulsion antiseptic, isothiazolone photog emulsion antiseptic, Radiation Chemistry, Photochemistry, and Photographic and Other Reprographic Processes: Silver Halide Photographic Chemistry and Processes and other aspects.SDS of cas: 26172-54-3

On December 21, 1984, Mine, Kyomitsu; Irie, Soichiro; Hirao, Yotaro; Nagumo, Toshio; Kawaguchi, Yasushi; Kobayashi, Yayoi published a patent.SDS of cas: 26172-54-3 The title of the patent was Antiseptic treatment of silver halide photographic hydrophilic colloid layers. And the patent contained the following:

A phenol derivative I (R = halo, C1-6 alkyl, lower alkoxycarbonyl, CO2H; n = 0-5) and a compound of formula II (R1 = H, alkyl, cycloalkyl, alkenyl, aralkyl, aryl, heterocyclyl, alkylamido, arylthioamido, alkylthioamido, alkysulfamido, arylsulfamido; R2,R3 = H, halo, alkyl, cycloalkyl, aryl, heterocyclyl, CN, alkylthio, arylthio, alkylsulfoxy, alkylsulfonyl) are added to Ag halide photog. hydrophilic colloid layers as antiseptic agents. Thus, phenol and II (R1 = CONHMe; R2 = Br; R3 = H) were added to a Ag(Br, I) emulsion for x-ray films. The emulsion showed excellent antiseptic property (tested by using Acinetobacters) without degradation of sensitivity and other photog. characteristics. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).SDS of cas: 26172-54-3

The Article related to antiseptic treatment photog emulsion, phenol photog emulsion antiseptic, isothiazolone photog emulsion antiseptic, Radiation Chemistry, Photochemistry, and Photographic and Other Reprographic Processes: Silver Halide Photographic Chemistry and Processes and other aspects.SDS of cas: 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com