On November 23, 1972, Miller, George Allen; Weiler, Ernest Dieter published a patent.Formula: C4H6ClNOS The title of the patent was Pesticidal isothiazolinone metal salt complexes. And the patent contained the following:
Fifty-six title compounds [Im.MXn; R = H or Cl; R1 = H or Me; RR1 = CH:CHCH:CH; R2 = H, C1-10 normal or branched alkyl, Ph, m-ClC6H4, p-MeC6H4CH2, or p-ClC6H4CH2CH2; M = Ca, Cd, Co, Cr, Cu, Fe, Hg, Mg, Mn, Ni, Sn, or Zn; X = e.g., Cl, SO4, or Br; m = 1 or 2; n = 1-3] were prepared in .leq.100% yield by reaction of I or I-HX with MXn or MO, resp. I were used as algicides, bactericides, fungicides, herbicides, insecticides, and slimicides, e.g., in cooling towers and paper mills or against mildew in paints. Thus, 2-methyl-3-isothiazolone [2682-20-4] in EtOH was added to ZnCl2 in EtOH and the mixture stirred 30 min to give 92% bis(2-methyl-3-isothiazolone zinc (II) chloride (II) [38897-06-2]. 2-Methyl-3-isothiazolone-HCl [26172-54-3] and ZnO in MeOH were stirred 24 hr to give 94% II. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Formula: C4H6ClNOS
The Article related to isothiazolinone salt pesticide, algicide isothiazolinone, bactericide isothiazolinone, fungicide isothiazolinone, herbicide isothiazolinone, insecticide isothiazolinone, slimicide isothiazolinone and other aspects.Formula: C4H6ClNOS
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com