Davis, Franklin A’s team published research in Journal of Organic Chemistry in 1992-11-20 | 104322-63-6

Journal of Organic Chemistry published new progress about Amino acids, hydroxy Role: SPN (Synthetic Preparation), PREP (Preparation). 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Computed Properties of 104322-63-6.

Davis, Franklin A.; Reddy, R. Thimma; Reddy, Rajarathnam E. published the artcile< Asymmetric synthesis of sulfinimines: applications to the synthesis of nonracemic β-amino acids and α-hydroxyl β-amino acids>, Computed Properties of 104322-63-6, the main research area is asym synthesis sulfinimine; beta amino acid; hydroxy beta amino acid; stereoselective oxidation sulfenimine dichlorocamphoryloxaziridine; chlorocamphoryloxaziridine stereoselective oxidation sulfenimine; camphoryloxaziridine dichloro stereoselective oxidation sulfenimine; oxaziridine dichlorocamphoryl stereoselective oxidation sulfenimine.

Asym. oxidation of sulfenimines I (Ar = Ph, R = H, X = H, MeO; Ar = p-tolyl, R = Me, X = H) with chiral oxaziridines II or III affords sulfinimines IV or V (88-90% ee), which are chiral ammonia imine synthons useful in the enantioselective synthesis of β-amino acids and α-hydroxy β-amino acids such as the C-13 side chain of taxol.

Journal of Organic Chemistry published new progress about Amino acids, hydroxy Role: SPN (Synthetic Preparation), PREP (Preparation). 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Computed Properties of 104322-63-6.

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com