The author of 《Microwave-assisted synthesis of benzisothiazoles and benzisoselenazoles》 were Rais, Afsha; Ankati, Haribabu; Biehl, Ed. And the article was published in Trends in Heterocyclic Chemistry in 2009. Related Products of 35272-19-6 The author mentioned the following in the article:
A microwave-mediated preparation and possible mechanism of benzisothiazole and benzisoselenazole formation are presented. The synthesis of the target compounds [i.e., 3-methyl-1,2-benzisothiazol-5-amine, 3-methyl-1,2-benzisoselenazol-5-amine] was achieved using sulfur or selenium and 1-(2-chloro-5-nitrophenyl)ethanone and ammonium acetate as starting materials. The experimental process involved the reaction of 3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6Related Products of 35272-19-6)
3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6) belongs to isothiazole. Various penicillins and cephalosporins having an isothiazole ring system have shown considerable antibacterial efficacy against Gram-positive and Gram-negative bacteria. Related Products of 35272-19-6Many compounds with an isothiazole scaffold demonstrated a wide range of biological profiles, including antiinflammatory, antithrombotic, and anticonvulsive agents.
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com