Peng, Yu; Luo, Zhen-Biao; Zhang, Jian-Jian; Luo, Long; Wang, Ya-Wen published the artcile< Collective synthesis of several 2,7'-cyclolignans and their correlation by chemical transformations>, Recommanded Product: (4aS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide, the main research area is stereoselective cyclization aristoligone aristoligol preparation; cyclolignan cyclogalgravin linchpin redox neolignan kadangustin plant cyclization.
Collective synthesis of antimalarial 2,7′-cyclolignans has been stereoselectively achieved employing (±)-cyclogalgravin as a linchpin through a series of functional group conversions, including redox reactions. Interestingly, (±)-cyclogalgravin can be correlated with the neolignan (±)-kadangustin J isolated from a different plant source, through a highly efficient dehydrative cyclization reaction with excellent diastereotopic differentiation of the veratryl group and concomitant construction of the C1-C7 bond. It is noteworthy that the first total synthesis of stereo-divergent (±)-8,8′-epi-aristoligone, (±)-8′-epi-aristoligone, (±)-8′-epi-8-OH-aristoligone, and (±)-8′-epi-aristoligol was demonstrated.
Organic & Biomolecular Chemistry published new progress about Cyclization, stereoselective. 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Recommanded Product: (4aS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide.
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com