Josien, Hubert; Curran, Dennis P. published the artcile< Synthesis of (S)-mappicine and mappicine ketone via radical cascade reaction of isonitriles>, Safety of (4aS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide, the main research area is mappicine synthesis; radical cascade isonitrile.
(S)-mappicine (I) and mappicine ketone were prepared from Me acetoacetate by a strategy featuring a radical cascade reaction of II with Ph isonitrile as the key step. The introduction of the hydroxy group of (S)-mappicine occurred with moderate selectivity through asym. hydroxylation.
Tetrahedron published new progress about Radical cyclization. 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Safety of (4aS,7R,8aS)-9,9-Dimethyltetrahydro-4H-4a,7-methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide.
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com