Davis, Franklin A.; Kumar, Anil published the artcile< Kinetic resolution in the asymmetric hydroxylation of enolates. Stereospecific synthesis of (2S,3R)-(-)-verrucarinolactone>, Application of C10H15NO3S, the main research area is methylvalerolactone asym hydroxylation camphorylsulfonyloxaziridine; verrucarinolactone stereoselective preparation.
Asym. hydroxylation of (±)-3-methylvalerolactone (I; R = H) with substoichiometric amounts of the (-)-(camphorylsulfonyl)oxaziridine affords (2S,3R)-(-)-verrucarinolactone (I; R = HO) in 60% ee, which on crystallization is obtained enantiomerically pure. This result not only represents a highly efficient stereospecific synthesis of an important lactone, but also demonstrates the application of kinetic resolution and asym. hydroxylation in the synthesis of enantiomerically enriched α-hydroxy carbonyl compounds having multiple stereocenters.
Journal of Organic Chemistry published new progress about 104322-63-6. 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Application of C10H15NO3S.
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com