In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called High-yield regioselective thiation of biologically important pyrimidinones, dihydropyrimidinones and their ribo, 2′-deoxyribo and 2′,3′-dideoxyribo nucleosides, published in 1993-02-28, which mentions a compound: 6307-44-4, mainly applied to pyrimidinone regioselective thiation Lawesson reagent; nucleoside pyrimidinone regioselective thiation Lawesson reagent, Reference of 2-Amino-6-methylpyrimidine-4-thiol.
Convenient and high-yield regioselective thiation procedures based on the use of the Lawesson reagent in different solvents, are described for conversion of the 2- and 4-keto, and 2,4-diketo pyrimidines to the corresponding 2(4)-thio, and 2,4-dithio, derivatives This method is applicable to thiation of the 4-keto groups of 5,6-dihydropyrimidinones and pyrimidine nucleosides. The mild reaction conditions employed are such that it is the method of choice for compounds with labile glycosidic bonds, of choice for compounds with labile glycosidic bonds, such as 5,6-dihydropyrimidine nucleosides and the 2′,3′-dideoxynucleosides currently of interest as antiretroviral, including anti-HIV, agents.
The article 《High-yield regioselective thiation of biologically important pyrimidinones, dihydropyrimidinones and their ribo, 2′-deoxyribo and 2′,3′-dideoxyribo nucleosides》 also mentions many details about this compound(6307-44-4)Reference of 2-Amino-6-methylpyrimidine-4-thiol, you can pay attention to it, because details determine success or failure
Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com