So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Zhang, Jian; Chen, Shumei; Nieto, Ruben A.; Wu, Tao; Feng, Pingyun; Bu, Xianhui researched the compound: (1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid( cas:560-09-8 ).Safety of (1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid.They published the article 《A Tale of Three Carboxylates: Cooperative Asymmetric Crystallization of a Three-Dimensional Microporous Framework from Achiral Precursors》 about this compound( cas:560-09-8 ) in Angewandte Chemie, International Edition. Keywords: manganese formate adamantanedicarboxylate polymer preparation chirality camphoric glutamic; crystal structure manganese formate adamantanedicarboxylate chirality induction; gas adsorption manganese formate adamantanedicarboxylate polymer complex. We’ll tell you more about this compound (cas:560-09-8).
Sym. crystallization of 3D porous materials constructed entirely from achiral building blocks by using enantiopure organic acids or amino acids as chirality-inducing agents is reported. Thus, the presence of D-camphor led to (+)-Mn3(HCOO)4(adc) (adc = 1,3-adamantanedicarboxylate), while L-camphor resulted in (-)-Mn3(HCOO)4(adc), which were characterized by x-ray crystallog. The chiral induction agent is essential to initiate the nucleation of the chiral crystals. The chirality control seems to be achieved through cooperative binding between enantiopure chiral reagents and achiral structural building units. Enantiopure chiral reagents control the absolute chirality of the crystals by participating in the nucleation and crystallization processes, but are later replaced with achiral ligands in the resulting crystals.
Although many compounds look similar to this compound(560-09-8)Safety of (1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid, numerous studies have shown that this compound(SMILES:CC1(C)[C@@H](CC[C@]1(C)C(O)=O)C(O)=O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com