Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid, is researched, Molecular C10H16O4, CAS is 560-09-8, about Synthesis of D-camphor based γ-amino acid (1S,3R)-3-amino-2,2,3-trimethylcyclopentane carboxylic acid.Recommanded Product: (1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid.
Synthesis of a γ-amino acid derived from (1R,3S)-camphoric acid is described. D-(+)-Camphoric anhydride, prepared from D-(+)-camphoric acid by treatment with methanesulfonyl chloride and triethylamine, was reacted with benzyl alc. and catalytic DMAP, and subsequently reacted in a Curtius rearrangement to afford the corresponding carbamate derivative This derivative was converted to the desired γ-amino acid through hydrogenolysis.
As far as I know, this compound(560-09-8)Recommanded Product: (1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com