Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid, is researched, Molecular C10H16O4, CAS is 560-09-8, about HPLC detection and evaluation of chiral compounds with a laser-based chiroptical detector.Formula: C10H16O4.
The sensitivity and ruggedness of chiroptical detectors have improved considerably during the past decade. The authors examine >230 chiral compounds using the latest laser-based polarimetry detector for HPLC. They also examine the relation between optical rotation at the detector wavelength of 675 nm and the sodium D line. The authors consider the sensitivity, linear dynamic range, and effect of solvent composition on rotation and its general use as an HPLC detector for chiral compounds
In addition to the literature in the link below, there is a lot of literature about this compound((1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid)Formula: C10H16O4, illustrating the importance and wide applicability of this compound(560-09-8).
Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com