Lee, Chang-Seok; Oh, Seong Ho; Ryu, Eun-Jung; Kim, Mu-Yong; Paek, Kyung-Sook published the article 《Synthesis and antibacterial activities of novel C(3)-aminopyrimidinyl substituted cephalosporins》. Keywords: cephalosporin aminopyrimidinylthio antibacterial antimicrobial preparation; beta lactam aminopyrimidinylthio preparation.They researched the compound: 2-Amino-6-methylpyrimidine-4-thiol( cas:6307-44-4 ).COA of Formula: C5H7N3S. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:6307-44-4) here.
A new class of cephalosporins with C(3)-aminopyrimidinylthio substituents was prepared and found to exhibit well balanced activities against Gram-neg. and Gram-pos. bacteria. The MIC data on some of these new β-lactams, e.g., I and II, prove that this type of cephalosporin deserves further evaluation as new antibiotics against respiratory tract pathogens.
This literature about this compound(6307-44-4)COA of Formula: C5H7N3Shas given us a lot of inspiration, and I hope that the research on this compound(2-Amino-6-methylpyrimidine-4-thiol) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com