Synthetic Route of C10H12ClIN2O2. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: tert-Butyl (6-chloro-4-iodopyridin-3-yl)carbamate, is researched, Molecular C10H12ClIN2O2, CAS is 400777-00-6, about Discovery of potent, balanced and orally active dual NK1/NK3 receptor ligands.
During a program directed at selective NK1 receptor antagonists, we serendipitously discovered an NK1 receptor ligand with addnl. affinity for the NK3 receptor. Recognising an opportunity for a drug discovery program aiming for dual NK1/NK3 receptor antagonists, we prepared a series of analogs from a novel, versatile building block. From this series emerged compounds with high and balanced affinities for the NK1 and the NK3 receptors. Typical representatives of this series were active in the gerbil foot tapping assay after oral administration.
There is still a lot of research devoted to this compound(SMILES：O=C(OC(C)(C)C)NC1=C(I)C=C(Cl)N=C1)Synthetic Route of C10H12ClIN2O2, and with the development of science, more effects of this compound(400777-00-6) can be discovered.
Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com