So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Mueller, Detlef M.; Strack, Erich researched the compound: (1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid( cas:560-09-8 ).HPLC of Formula: 560-09-8.They published the article 《Resolution of the racemates of DL-carnitine》 about this compound( cas:560-09-8 ) in Hoppe-Seyler’s Zeitschrift fuer Physiologische Chemie. Keywords: carnitine resolution camphorate; tartrate resolution carnitine; racemate carnitine resolution. We’ll tell you more about this compound (cas:560-09-8).
A rational and cheap method is reported for the direct resolution of DL-carnitine. D-(+)-Camphoric acid, L-(-)-camphoric acid, dibenzoyl-D-(-)-tartaric acid, or L-(+)-tartaric acid were used to sep. DL-carnitine into its optically active components. Resolution was achieved by repeated fractional crystallization in alc. solution with the appropriate acid, or by combined fractionation with a suitable pair of acids. The resulting salts can be decomposed quant. with water, dilute acids, ether/water, or ion exchanger, to give pure, optically active carnitines. The optically active acids may also be recovered pure and used again for racemate separation
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Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com