Month: February 2022

Recommanded Product: Benzoic anhydride. I found the field of Chemistry very interesting. Saw the article Air-stable binuclear Titanium(IV) salophen perfluorobutanesulfonate with zinc power catalytic system and its application to C-S and C-Se bond formation published in 2020, Reprint Addresses Wei, JC; Li, NB (corresponding author), Shanxi Med Univ, Basic Med Coll, Taiyuan 030001, Peoples R China.; Xu, XH (corresponding author), Hunan Univ, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China.. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride.

An air-stable mu-oxo-bridged binuclear Lewis acid of titanium(IV) salophen perfluorobutanesulfonate [{Ti(salophen)H2O)(2)O][OSO2C4F9](2) (1) was successfully synthesized by the reaction of Ti-IV(salophen)Cl-2 with AgOSO2C4F9 and characterized by techniques such as IR, NMR and HRMS. This complex was stable open to air over a year, and exhibited good thermal stability and high solubility in polar organic solvents. The complex also had relatively strong acidity with a strength of 0.8 < Ho <= 3.3, and showed high catalytic efficiency towards various C-S and C-Se bond formations in the presence of zinc power. This catalytic system affords a mild and efficient approach to synthesis of thio- and selenoesters, alpha-arylthio- and seleno-carbonyl compounds, and thio- and selenoethers. (C) 2019 Elsevier Ltd. All rights reserved. About Benzoic anhydride, If you have any questions, you can contact Wang, LX; Qiao, J; Wei, JC; Liang, ZW; Xu, XH; Li, NB or concate me.. Recommanded Product: Benzoic anhydride

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Recommanded Product: 99-04-7. In 2019.0 J ORG CHEM published article about RING-OPENING REACTION; STEREOSELECTIVE-SYNTHESIS; NEBER REARRANGEMENT; TERMINAL ALKYNES; CYCLOADDITION; CYCLIZATION; AZIRINES; ACIDS; OXAZOLES; ACCESS in [Xu, Fen; Si, Xiao-Ju; Song, Yuan-Yuan; Wang, Xing-Dong; Liu, Chun-Sen; Geng, Peng-Fei; Du, Miao] Zhengzhou Univ Light Ind, Coll Mat & Chem Engn, Zhengzhou 450002, Henan, Peoples R China in 2019.0, Cited 60.0. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.

A Pd-catalyzed ring-opening reaction of 2H-azirines with carboxylic acids was developed. This reaction undergoes nucleophilic addition between 2,3-diaryl-2H-azirines and carboxylic acids followed by C-N single-bond cleavage and a subsequent thermal rearrangement. This method enables the rapid construction of valuable alpha-amido ketone derivatives with high atomic efficiency and superb functional group tolerance.

Recommanded Product: 99-04-7. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

An article Electrooxidative 1,2-Bromoesterification of Alkenes with Acids and N-Bromosuccinimide WOS:000465644300065 published article about ASYMMETRIC INTERMOLECULAR BROMOESTERIFICATION; ELECTROCHEMICAL SYNTHESIS; OXIDATIVE AMINATION; BOND-CLEAVAGE; METAL; REAGENT; FUNCTIONALIZATION; THIAZOLOPYRIDINES; ELECTROSYNTHESIS; BENZOTHIAZOLES in [Wan, Chao; Song, Ren-Jie; Li, Jin-Heng] Nanchang Hangkong Univ, Key Lab Jiangxi Prov Persistent Pollutants Contro, Nanchang 330063, Jiangxi, Peoples R China; [Li, Jin-Heng] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China in 2019, Cited 92. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7. Formula: C8H8O2

A simple three-component 1,2-bromoesterification of alkenes with acids and N-bromosuccinimide under electrochemical oxidative conditions is described. This transformation enables the construction of beta-bromoalkyl esters via oxidative C-Br/C-O difunctionalization, where a variety of alkenes, including styrenes and cycloolefins, were well tolerated to react efficiently with a wide range of acids, such as aromatic acids, aliphatic acids, and amino acids.

Formula: C8H8O2. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

I found the field of Chemistry very interesting. Saw the article Cytotoxicity and ROS production of novel Pt(IV) oxaliplatin derivatives with indole propionic acid published in 2019. Computed Properties of C14H10O3, Reprint Addresses Erxleben, A (corresponding author), Natl Univ Ireland, Sch Chem, Galway, Ireland.; Montagner, D (corresponding author), Maynooth Univ, Dept Chem, Maynooth, Kildare, Ireland.. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride

The coordination of biologically active moieties to the axial positions of Pt(IV) derivatives of Pt(II) anticancer drugs allows the co-delivery and simultaneous activation of two pro-drugs for combination therapy. Pt(IV) complexes with a redox modulator as an axial ligand can kill cancer cells by a mechanism combining DNA platination and generation of oxidative stress. In this study we evaluated the cytotoxicity of Pt(IV) complexes based on the oxaliplatin scaffold and the pro-oxidant indole-3-propionate in cisplatin-sensitive and cisplatin-resistant ovarian cancer cells. A series of five complexes was synthesized and characterized by H-1 and Pt-195 NMR spectroscopy, IR spectroscopy, mass spectrometry and elemental analysis; trans-[Pt(DACH)(ox)(IPA)(OH)] (1), trans-[Pt(DACH)(ox)(IPA)(2)] (2), trans-[Pt(DACH)(ox)(IPA)(bz)] (3), trans-[Pt(DACH)(ox)(IPA)(suc)] (4), and trans-[Pt(DACH)(ox)(IPA)(ac)] (5) (DACH = 1,2-diaminocyclohexane (1R, 2R)-(-), ox = oxalate, IPA = indole 3-propionate, bz = benzoate, suc = succinate and ac = acetate). The complexes were shown to produce cellular reactive oxygen species (ROS) in a time-dependent manner. The most potent ROS producer, complex 1, also elicited the highest cytotoxicity. Complex 1 was shown to form the mono-and bis-adducts [Pt(DACH)(guanosine)( OH)](+) and [Pt(DACH)(guanosine)(2)](2+) in the presence of ascorbic acid, suggesting that on activation the released oxaliplatin will interact with DNA.

Bye, fridends, I hope you can learn more about C14H10O3, If you have any questions, you can browse other blog as well. See you lster.. Computed Properties of C14H10O3

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Recently I am researching about NONLINEAR-OPTICAL ANALYSES; EXCITED-STATE; SELECTIVE DETECTION; ANTIPROLIFERATIVE ACTIVITIES; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; PI-STAR; CHEMOSENSOR; ABSORPTION; COMPLEXES, Saw an article supported by the Bitlis Eren University Research FoundationBitlis Eren University [BEBAP-2014.05]. Published in SPRINGER/PLENUM PUBLISHERS in NEW YORK ,Authors: Sidir, YG; Aslan, C; Berber, H; Sidir, I. The CAS is 93-02-7. Through research, I have a further understanding and discovery of 2,5-Dimethoxybenzaldehyde. Category: isothiazole

The electronic structure and electronic transitions of four new mono Schiff base derivatives are interpreted by using absorption and fluorescence spectra including 28 different solution medium. Electrical dipole moments have been found by means of four different quantum mechanical methods based on solvatochromic shifts like Lippert-Mataga, Bakhshiev, modified Bilot-Kawski, and Reichardt methods. Quantitative researches of solvent-solute interactions are done by using Kamlet-Taft and Catalan parameters. In absorption and fluorescence spectra, bathochromic shift occurs with dispersion-polarization forces effect. The electronic transitions and electronic structure of these molecules have changed to dependent on solvent medium property. HOMO, LUMO, MEP, and SAS were calculated using B3LYP/6-311G(d,p) level of theory. Solvatochromism, photophysical properties, and electronic structure were discussed in detail. The dipole moments in ground-state and excited-state have not almost change.

Welcome to talk about 93-02-7, If you have any questions, you can contact Sidir, YG; Aslan, C; Berber, H; Sidir, I or send Email.. Category: isothiazole

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Recommanded Product: 385-00-2. Authors Wang, R; Liu, H; You, YY; Wang, XY; Lv, BB; Cao, LQ; Xue, JY; Xu, YG; Shi, L in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Wang, Ru; Liu, Hu; You, Yuan-Yuan; Wang, Xin-Yu; Lv, Bing-Bing; Cao, Li-Qin; Xu, Yun-Gen; Shi, Lei] China Pharmaceut Univ, Dept Med Chem, Jiangsu Key Lab Drug Design & Optimizat, Nanjing 210009, Peoples R China; [Xue, Jia-Yu] Jiangsu Prov & Chinese Acad Sci, Inst Bot, Jiangsu Prov Key Lab Plant Ex Situ Conservat, Nanjing 210014, Peoples R China in 2021, Cited 29. The Name is 2,6-Difluorobenzoic acid. Through research, I have a further understanding and discovery of 385-00-2

VEGF/VEGFR-2 signaling plays a critical part in tumor angiogenesis. Inhibition of this pathway has been considered as a promising approach for cancer treatment. In this work, a series of 6,7-dimethoxy-4-anilinoquinazoline derivatives bearing diarylamide moiety were designed, synthesized and evaluated as potent inhibitors of VEGFR-2 kinase. Their in vitro antiproliferation activities against two human cancer cell lines Hep-G2 and MCF-7 have also been determined. Among them, compound 14b exhibited the most potent inhibitory activity against VEGFR-2 with IC50 value of 0.016 +/- 0.002 mu M and it showed the most potent antiproliferative effect against Hep-G2 and MCF-7 with IC50 values at low-micromolar range. Molecular docking studies revealed that these compounds represented by the most potent compound 14b could bind well to the ATP-binding site of VEGFR-2, which suggested that compound 14b could be a potential anticancer agent targeting VEGFR-2.

Recommanded Product: 385-00-2. Bye, fridends, I hope you can learn more about C7H4F2O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Application In Synthesis of 1,3-Dimethoxybenzene. Authors Ojah, EO; Moronkola, DO; Ajiboye, CO; Yusuf, TL; Adeniyi-Akee, MA in TAYLOR & FRANCIS LTD published article about in [Ojah, Emmanuel Onah; Moronkola, Dorcas Olufunke; Ajiboye, Clement Odunayo] Univ Ibadan, Dept Chem, Ibadan, Nigeria; [Ojah, Emmanuel Onah] Mt Top Univ, Dept Chem Sci, Coll Basic & Appl Sci, Makogi Oba, Ogun State, Nigeria; [Yusuf, Tunde Lewis] Univ KwaZulu Natal, Sch Chem & Phys, Private Bag X54001,Westville Campus, ZA-4000 Durban, South Africa; [Adeniyi-Akee, Mukaram Akintunde] Igbined Univ, Dept Pharmaceut Chem, Coll Pharm, Okada, Edo State, Nigeria in 2021, Cited 47. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0

The chemical composition of essential oils (EOs) isolated by hydrodistillation from Pterocarpus soyauxii Taub. root wood and root bark were determined for the first time by GC/MS analysis. The EOs gave a percentage yield (w/w) of 0.34 % and 0.31 % for root wood and root bark respectively. A total of 60 compounds accounting for 86.1 % of the root wood EO composition were identified with monoterpenes (45.4 %) and sesquiterpenes (14.7 %) as predominant constituents. Root bark EO gave 53 identified constituents which make up about 78.5 % of the EO dominated by non-terpenes (23.4 %) and alkanes (14.1 %). The EOs are good sources of limonene (16.9 %), gamma-terpinene (9.8 %) and p-cymene (6.70 %). The anti-diabetic (alpha-amylase and alpha-glucosidase models) and antioxidant activities (DPPH and H2O2 models) of EOs were evaluated in comparison with standard drugs. Alpha-amylase inhibition gave IC50 values (mg/mL) of 0.0493 and 0.0471 for root wood and root bark EOs respectively, compared to acarbose the standard anti-diabetic drug (0.0401) while alpha-glucosidase assay gave IC50 values (mg/mL) of 0.0517 and 0.0486 for root wood and root bark EOs respectively, compared with acarbose (0.0418). In the DPPH antioxidant assay, root bark EO showed higher activity (0.157 mg/mL) compared to root wood EO (0.159 mg/mL) while Root wood and root bark EOs had IC(50 )values (mg/mL) of 0.157 and 0.171 respectively using the H2O2 model. Results revealed the presence of chemical constituents in the EOs which could be responsible for activities expressed by the plant.

Application In Synthesis of 1,3-Dimethoxybenzene. Bye, fridends, I hope you can learn more about C8H10O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

An article Efficient Synthesis of Diarylmethylamines via Lewis Acid Catalyzed Friedel-Crafts Reactions of Donor-Acceptor Aziridines with N,N-Dialkylanilines WOS:000502820600012 published article about ASYMMETRIC 3+2 CYCLOADDITION; CHIRAL DIENE LIGANDS; H BOND ARYLATION; N-TOSYLAZIRIDINES; C-ARYLATION; N,N-DIALKYL-3-VINYLANILINES; DERIVATIVES; FUNCTIONALIZATION; TOSYLARYLIMINES; ALDEHYDES in [Kim, Yerin; Kwon, Yong Il; Kim, Sung-Gon] Kyonggi Univ, Dept Chem, 154-42 Gwanggyosan Ro, Suwon 16227, South Korea in 2020, Cited 57. Recommanded Product: 1,3-Dimethoxybenzene. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0

A method for efficient and mild synthesis of diarylmethylamine scaffold, via Lewis acid catalyzed Friedel-Crafts reaction of donor-acceptor aziridines with N,N-dialkylanilines to afford a biologically important diarylmethylamine derivatives in high yields (up to 88%), is presented. This reaction is suitable for the synthesis of various diarylmethylamine derivatives and has a broad scope for electron-rich arenes, including dimethoxybenzene.

Recommanded Product: 1,3-Dimethoxybenzene. Welcome to talk about 151-10-0, If you have any questions, you can contact Kim, Y; Kwon, YI; Kim, SG or send Email.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

An article Direct Amidation of Carboxylic Acids with Nitroarenes WOS:000494562600063 published article about PEPTIDE COUPLING REAGENTS; SECONDARY AMIDES; CADOGAN REACTION; TRANSAMIDATION; ARYL; INHIBITORS; CHEMISTRY; AMINES; AMINOCARBONYLATION; HYDROAMINATION in [Cheung, Chi Wai; Ma, Jun-An] Tianjin Univ, Tianjin Key Lab Mol Optoelect Sci, Dept Chem, Tianjin 300072, Peoples R China; Tianjin Univ, Tianjin Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300072, Peoples R China; Joint Sch NUS & TJU, Int Campus Tianjin Univ, Fuzhou 350207, Fujian, Peoples R China in 2019, Cited 87. Safety of 3-Methylbenzoic acid. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

N-Aryl amides are an important class of compounds in pharmaceutical and agrochemical chemistry. Rapid and low-cost synthesis of N-aryl amides remains in high demand. Herein, we disclose an operationally simple process to access N-aryl amides directly from readily available nitroarenes and carboxylic acids as coupling substrates. This method involves the in situ activation of carboxylic acids to acyloxyphosphonium salt for one-pot amidation, without the need for isolation of the corresponding synthetic intermediates. Furthermore, the ease of preparation and workup allow the quick and efficient synthesis of a wide range of N-aryl amides, including several amide-based druglike and agrochemical molecules.

Welcome to talk about 99-04-7, If you have any questions, you can contact Wang, SP; Cheung, CW; Ma, JA or send Email.. Safety of 3-Methylbenzoic acid

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

An article Insights into the mechanism of nonradical reactions of persulfate activated by carbon nanotubes: Activation performance and structure-function relationship WOS:000468253500040 published article about REDUCED GRAPHENE OXIDE; CATALYTIC-OXIDATION; SINGLET OXYGEN; GRAPHITIZED NANODIAMONDS; HETEROGENEOUS CATALYSIS; ORGANIC POLLUTANTS; DEGRADATION; KINETICS; HEAT; UV in [Cheng, Xin; Guo, Hongguang; Zhang, Yongli; Yang, Bo] Sichuan Univ, Coll Architecture & Environm, Chengdu 610065, Sichuan, Peoples R China; [Guo, Hongguang; Korshin, Gregory V.] Univ Washington, Dept Civil & Environm Engn, Box 352700, Seattle, WA 98195 USA in 2019, Cited 82. Safety of Benzoic anhydride. The Name is Benzoic anhydride. Through research, I have a further understanding and discovery of 93-97-0

This study aimed to elucidate the intrinsic mechanisms of PS activation by carbon nanotubes (CNTs). Singlet oxygen generation (O-1(2)) and direct CNTs-mediated electron transfer were hypothesized to be two major pathways of the oxidation of 2,4-dichlorophenol (2,4-DCP) by PS in the presence of both unmodified and modified CNTs. For the first time, roles of CNT active sites responsible for PS activation were determined using CNT derivatization and structural characterization. By selectively deactivating the carbonyl, hydroxyl or carboxylic groups on CNTs surface and linear sweep voltammetry (LSV) analysis, -C=0 groups were determined to be the main active sites contributing to the direct electron transfer oxidation, while singlet oxygen was generated at CNTs defects. Subsequent UV irradiation was shown to cause the recovery of surface defects with I-D/I-G of CNTs increasing by 21%. This resulted in the regeneration of the performance for the coupled system and allowed for multi-cycle activation of PS by CNTs. These results suggest that CNTs/PS system combined with regeneration based on UV irradiation can be used as an effective alternative process for continuous degradation of recalcitrant aqueous contaminants through the non-radical mechanism. (C) 2019 Elsevier Ltd. All rights reserved.

Safety of Benzoic anhydride. Welcome to talk about 93-97-0, If you have any questions, you can contact Cheng, X; Guo, HG; Zhang, YL; Korshin, GV; Yang, B or send Email.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com