Application In Synthesis of 2,5-Dimethoxybenzaldehyde. Krishnammagari, SK; Balwe, SG; Kim, JS; Lim, KT; Jeong, YT in [Krishnammagari, Suresh Kumar; Balwe, Sandip Gangadhar; Kim, Jong Su; Lim, Kwon Taek; Jeong, Yeon Tae] Pukyong Natl Univ, Dept Image Sci & Engn, Busan 608737, South Korea published A one-pot four-component domino protocol for the synthesis of indole and coumarin containing pyridine-3-carbonitrile derivatives in 2019.0, Cited 42.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.
An efficient and simple protocol for the synthesis of a new class of diversely functionalized novel indole and coumarin containing pyridine-3-carbonitrile derivatives has been described through one-pot four-component condensation reaction of 3-(1H-indol-3-yl)-3-oxopropanenitrile, various aldehydes, 3-acetyl-2H-chromenones, and ammonium acetate in acetic acid conditions. The present new methodology offers several advantages such as short reaction time, easy experimental work-up, and good product yield, and endures the substrate diversity and operational simplicity under metal-free reaction conditions for the formation of C-C/C-N bonds. [GRAPHICS] .
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Reference:
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