Authors Wang, JN; Chen, SQ; Liu, ZW; Shi, XY in AMER CHEMICAL SOC published article about MEDIATED DIECKMANN CYCLIZATION; HIGHLY SUBSTITUTED INDANONES; H BOND ALKENYLATIONS; ASYMMETRIC-SYNTHESIS; NAZAROV CYCLIZATION; CARBOXYLIC-ACIDS; ACRYLIC-ACIDS; BENZOIC-ACIDS; N BOND; EFFICIENT in [Wang, Jia-Ni; Chen, Si-Qi; Liu, Zhong-Wen; Shi, Xian-Ying] Shaanxi Normal Univ, Sch Chem & Chem Engn, Res Ctr Appl Catalysis, Key Lab Macromol Sci Shaanxi Prov, Xian 710062, Shaanxi, Peoples R China in 2019, Cited 70. Safety of 3-Methylbenzoic acid. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7
The one-step strategy for the facile syntheses of structurally diverse 1-indanones in moderate to good isolated yields was developed via a ruthenium-catalyzed tandem coupling and cyclization of simple aromatic acids with alpha,beta-unsaturated ketones. The tandem cyclization involves one-pot sequential reactions of C-H activation, conjugate addition, Dieckmann condensation, Michael addition, intramolecular Aldol reaction, or hydrolysis. Switchable access to spiroindanones and 2-substituted 1-indanones could be achieved by manganese additive and H2O. Mn(II) additive is found to play an important role in this transformation, and a trace amount of water can promote the formation of 2-substituted 1-indanones. This process features the one-pot efficient construction of multiple C-C bonds, high step-economy, commercially available starting materials, and a broad substrate scope.
Safety of 3-Methylbenzoic acid. Welcome to talk about 99-04-7, If you have any questions, you can contact Wang, JN; Chen, SQ; Liu, ZW; Shi, XY or send Email.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com