Recently I am researching about DYNAMIC KINETIC RESOLUTION; CHALCOGEN-CHALCOGEN INTERACTIONS; ENANTIOSELECTIVE SYNTHESIS; PIVALIC ANHYDRIDE; ATROPOSELECTIVE SYNTHESIS; NONCOVALENT INTERACTIONS; DENSITY FUNCTIONALS; DIPHENYLACETIC ACID; CHIRAL BIARYLS; ALCOHOLS, Saw an article supported by the . COA of Formula: C14H10O3. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Munday, ES; Grove, MA; Feoktistova, T; Brueckner, AC; Walden, DM; Young, CM; Slawin, AMZ; Campbell, AD; Cheong, PHY; Smith, AD. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride
Axially chiral phenols are attractive targets in organic synthesis. This motif is central to many natural products and widely used as precursors to, or directly, as chiral ligands and catalysts. Despite their utility few simple catalytic methods are available for their synthesis in high enantiopurity. Herein the atropselective acylation of a range of symmetric biaryl diols is investigated using isothiourea catalysis. Studies on a model biaryl diol substrate shows that the high product er observed in the process is a result of two successive enantioselective reactions consisting of an initial enantioselective desymmetrization coupled with a second chiroablative kinetic resolution. Extension of this process to a range of substrates, including a challenging tetraorthosubstituted biaryl diol, led to highly enantioenriched products (14 examples, up to 98:2 er), with either HyperB(TM) or B-TM identified as the optimal catalyst depending upon the substitution pattern within the substrate. Computation has been used to understand the factors that lead to high enantiocontrol in this process, with maintenance of planarity to maximize a 1,5-S…O interaction within the key acyl ammonium intermediate identified as the major feature that determines atropselective acylation and thus product enantioselectivity.
COA of Formula: C14H10O3. Welcome to talk about 93-97-0, If you have any questions, you can contact Munday, ES; Grove, MA; Feoktistova, T; Brueckner, AC; Walden, DM; Young, CM; Slawin, AMZ; Campbell, AD; Cheong, PHY; Smith, AD or send Email.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com