Rokade, BV; Guiry, PJ in [Rokade, Balaji, V; Guiry, Patrick J.] Univ Coll Dublin UCD, Ctr Synth & Chem Biol CSCB, Synth & Solid State Pharmaceut Ctr SSPC, Sch Chem, Dublin 4, Ireland published Synthesis of alpha-Aryl Oxindoles by Friedel-Crafts Alkylation of Arenes in 2020, Cited 38. Formula: C8H10O2. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0.
alpha-Aryl oxindoles are accessed from isatin via a two-step procedure involving a phospha-Brook rearrangement and a Friedel-Crafts alkylation in a one-pot procedure. The use of 1,1,1,3,3,3-hexafluoro-2-propanol as solvent significantly extended the reaction substrate scope to include relatively less electron-rich arenes including benzene. This new alkylation method is fast and straightforward and allows for the direct introduction of the oxindole moiety onto a range of aromatic compounds including phenols. Additionally, the application of arylated products was shown in decarboxylative asymmetric allylation and protonation.
Welcome to talk about 151-10-0, If you have any questions, you can contact Rokade, BV; Guiry, PJ or send Email.. Formula: C8H10O2
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com