Recently I am researching about SELECTIVE DEPROTECTION; PMB ETHERS; GLYCOCONJUGATE VACCINES; GLYCOPEPTIDE ANTIGENS; CHEMICAL-SYNTHESIS; PROSTATE-CANCER; P-METHOXYBENZYL; MILD; OLIGOSACCHARIDES; CONJUGATE, Saw an article supported by the National Institutes of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA [1R35GM133602]; Mass Spectrometry Research Center at Vanderbilt University; NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [R35GM133602] Funding Source: NIH RePORTER. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Keith, DJ; Townsend, SD. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride. Application In Synthesis of Benzoic anhydride
Zwitterionic polysaccharides (ZPSs) activate T-cell-dependent immune responses by major histocompatibility complex class II presentation. Herein, we report the first synthesis of a Morganella morganii ZPS repeating unit as an enabling tool in the synthesis of novel ZPS materials. The repeating unit incorporates a 1,2-cis-alpha-glycosidic bond; the problematic 1,2-trans-galactosidic bond, Gal-beta-(1 -> 3)-GalNAc; and phosphoglycerol and phosphocholine residues which have not been previously observed together as functional groups on the same oligosaccharide. The successful third-generation approach leverages a first in class glycosylation of a phosphoglycerol-functionalized acceptor. To install the phosphocholine unit, a highly effective phosphocholine donor was synthesized.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com