I found the field of Chemistry very interesting. Saw the article Stereoelectronic Effects in Ligand Design: Enantioselective Rhodium-Catalyzed Hydrogenation of Aliphatic Cyclic Tetrasubstituted Enamides and Concise Synthesis of (R)-Tofacitinib published in 2019. SDS of cas: 93-97-0, Reprint Addresses Tang, WJ (corresponding author), Univ Chinese Acad Sci, Shanghai Inst Organ Chem, Ctr Excellence Mol Synth, State Key Lab Bioorgan & Nat Prod Chem, 345 Ling Ling Rd, Shanghai 200032, Peoples R China.; Yu, S; McWilliams, JC (corresponding author), Pfizer Global R&D, Chem Res & Dev, Eastern Point Rd, Groton, CT 06340 USA.. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride
We herein report the development of a conformationally defined, electron-rich, C-2-symmetric, P-chiral bisphosphorus ligand, ArcPhos, by taking advantage of stereoelectronic effects in ligand design. With the Rh-ArcPhos catalyst, excellent enantioselectivities and unprecedentedly high turnovers (TON up to 10 000) were achieved in the asymmetric hydrogenation of aliphatic carbocyclic and heterocyclic tetrasubstituted enamides, to generate a series of chiral cis-2-alkyl-substituted carbocyclic and heterocyclic amine derivatives in excellent enantiomeric ratios. This method also enabled an efficient and practical synthesis of the Janus kinase inhibitor (R)-tofacitinib.
SDS of cas: 93-97-0. Welcome to talk about 93-97-0, If you have any questions, you can contact Li, CX; Wan, F; Chen, Y; Peng, HN; Tang, WJ; Yu, S; McWilliams, JC; Mustakis, J; Samp, L; Maguire, RJ or send Email.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com