Product Details of 93-97-0. In 2020 BIOORG MED CHEM LETT published article about CHAGAS-DISEASE; RANDOMIZED-TRIAL; TRANSMISSION; BENZNIDAZOLE in [Koovits, Paul J.; Dessoy, Marco A.; Dias, Luiz C.] Univ Estadual Campinas, UNICAMP, Inst Chem, Rua Josue Castro S-N,Cidade Univ, BR-13083861 Campinas, SP, Brazil; [Matheeussen, An; Maes, Louis; Caljon, Guy] LMPH, Univ Pl 1, B-2610 Antwerp, Belgium; [Mowbray, Charles E.; Kratz, Jadel M.] DNDi, 15 Chemin Louis Dunant, CH-1202 Geneva, Switzerland in 2020, Cited 21. The Name is Benzoic anhydride. Through research, I have a further understanding and discovery of 93-97-0.
The structure-activity relationship of a 4-Azaindole-2-piperidine compound selected from GlaxoSmithKline’s recently disclosed open-resource Chagas box and possessing moderate activity against Trypanosoma cruzi, the parasite responsible for Chagas disease, is presented. Despite considerable medicinal chemistry efforts, a suitably potent and metabolically stable compound could not be identified to advance the series into in vivo studies. This research should be of interest to those in the area of neglected diseases and in particular anti-kinetoplastid drug discovery.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com