Recently I am researching about ENANTIOSELECTIVE SYNTHESIS; PHOSPHORUS LIGANDS; BRONSTED ACID; ALCOHOLS; ACTIVATION; BATCH; CATALYSIS; SECONDARY, Saw an article supported by the CERCA Programme/Generalitat de Catalunya; MINECO [CTQ2015-69136-R]; AGAUR/Generalitat de CatalunyaAgencia de Gestio D’Ajuts Universitaris de Recerca Agaur (AGAUR)Generalitat de Catalunya [2017 SGR 1139]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Lai, JS; Neyyappadath, RM; Smith, AD; Pericas, MA. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride. Name: Benzoic anhydride
A polystyrene-immobilized isothiourea has been applied to the enantioselective acylative kinetic resolution (KR) of monoacylated BINOL(s) with inexpensive isobutyric anhydride in batch and flow. High selectivity values (s=29 at 0 degrees C) and a remarkable stability of the catalytic system in the operation conditions have been recorded for unsubstituted BINOL. No significant loss of activity/selectivity is recorded after 10 consecutive KR cycles in batch. A continuous flow process has been implemented and operated with a 100 mmol (32.8 g) sample of racemic monoacetylated BINOL in dichloromethane solution in an 84 hours experiment with a packed bed reactor containing 1 g (f=0.37 mmol.g(-1)) of the functional resin (s=17-21). Residence time can be decreased to 10 min with the same reactor to achieve a conversion of 58% with a selectivity factor s=17 when a more highly functionalized catalyst (f=0.88 mmol.g(-1)) is used. This translates into a remarkable combined productivity of 5.5 mmol(prod) . mmol(cat)(-1) . h(-1).
Name: Benzoic anhydride. About Benzoic anhydride, If you have any questions, you can contact Lai, JS; Neyyappadath, RM; Smith, AD; Pericas, MA or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com