An article Phosphine-Free Ru-Catalyzed Regio- and Stereoselective Addition of Benzoic Acids to Trifluoromethylated Alkynes toward Facile Access to Trifluoromethyl Group-Substituted (E)-Enol Esters WOS:000518851600042 published article about CARBOXYLIC-ACIDS; INTERNAL ALKYNES; ENOL ESTERS; ANTI-MARKOVNIKOV; GOLD(I)-CATALYZED ADDITION; REGIOSELECTIVE SYNTHESIS; TERMINAL ALKYNES; HYDROCARBOXYLATION; ALKENES; SYSTEMS in [Liu, Guangyuan; Zhang, Xingxing; Kuang, Guanghua; Lu, Naihao; Fu, Yang; Peng, Yiyuan; Zhou, Yirong] Jiangxi Normal Univ, Coll Chem & Chem Engn, Key Lab Funct Small Organ Mol, Minist Educ, 99 Ziyang Rd, Nanchang 330022, Jiangxi, Peoples R China; [Xiao, Qiang] Jiangxi Sci & Technol Normal Univ, Jiangxi Key Lab Funct Organ Mol, 605 Fenglin Rd, Nanchang 330013, Jiangxi, Peoples R China; [Zhou, Yirong] Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, 13 Hangkong Rd, Wuhan 430030, Peoples R China in 2020, Cited 68. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7. Application In Synthesis of 3-Methylbenzoic acid
A combination of ruthenium catalyst with silver salt and copper salt was proved to be a highly efficient protocol for the direct addition reaction of benzoic acids with unsymmetrical trifluoromethylated internal alkynes. Diverse trifluoromethyl group-substituted (E)-enol esters were readily obtained for a broad substrate scope in moderate to good yields with excellent regio- and stereoselectivities under mild reaction conditions.
Welcome to talk about 99-04-7, If you have any questions, you can contact Liu, GY; Zhang, XX; Kuang, GH; Lu, NH; Fu, Y; Peng, YY; Xiao, Q; Zhou, YR or send Email.. Application In Synthesis of 3-Methylbenzoic acid
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