Hu, FP; Cui, XF; Lu, GQ; Huang, GS in [Hu, Fang-Peng; Cui, Xin-Feng; Lu, Guo-Qiang; Huang, Guo-Sheng] Lanzhou Univ, Dept Chem, State Key Lab Appl Organ Chem, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China published Base-promoted Lewis acid catalyzed synthesis of quinazoline derivatives in 2020.0, Cited 71.0. COA of Formula: C8H8O2. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.
A one-pot protocol has been developed for the synthesis of quinazolinones from amide-oxazolines with TsClviaa cyclic 1,3-azaoxonium intermediate and 6 pi electron cyclization in the presence of a Lewis acid and base. The process is operationally simple and has a broad substrate scope. This method provides a unique strategy for the construction of quinazolinones.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com