Quality Control of Benzoic anhydride. I found the field of Chemistry very interesting. Saw the article Synergistic Activation of Amides and Hydrocarbons for Direct C(sp(3))-H Acylation Enabled by Metallaphotoredox Catalysis published in 2020, Reprint Addresses Baik, MH; Hong, SH (corresponding author), Korean Adv Inst Sci & Technol KAIST, Dept Chem, Daejeon 34141, South Korea.; Baik, MH (corresponding author), Inst Basic Sci IBS, Ctr Catalyt Hydrocarbon Functionalizat, Daejeon 34141, South Korea.. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride.
The utilizations of omnipresent, thermodynamically stable amides and aliphatic C(sp(3))-H bonds for various functionalizations are ongoing challenges in catalysis. In particular, the direct coupling between the two functional groups has not been realized. Here, we report the synergistic activation of the two challenging bonds, the amide C-N and unactivated aliphatic C(sp(3))-H, via metallaphotoredox catalysis to directly acylate aliphatic C-H bonds utilizing amides as stable and readily accessible acyl surrogates. N-acylsuccinimides served as efficient acyl reagents for the streamlined synthesis of synthetically useful ketones from simple C(sp(3))-H substrates. Detailed mechanistic investigations using both computational and experimental mechanistic studies were performed to construct a detailed and complete catalytic cycle. The origin of the superior reactivity of the N-acylsuccinimides over other more reactive acyl sources such as acyl chlorides was found to be an uncommon reaction pathway which commences with C-H activation prior to oxidative addition of the acyl substrate.
Quality Control of Benzoic anhydride. About Benzoic anhydride, If you have any questions, you can contact Lee, GS; Won, J; Choi, S; Baik, MH; Hong, SH or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com