I found the field of Pharmacology & Pharmacy; Chemistry very interesting. Saw the article Synthesis and biofilm inhibition studies of 2-(2-amino-6-arylpyrimidin-4-yl) quinazolin-4(3H)-ones published in 2020.0. Name: 2,5-Dimethoxybenzaldehyde, Reprint Addresses Rasapalli, S (corresponding author), Univ Massachusetts Dartmouth, Dept Chem & Biochem, 285 Old Westport Rd, N Dartmouth, MA 02747 USA.. The CAS is 93-02-7. Through research, I have a further understanding and discovery of 2,5-Dimethoxybenzaldehyde
Synthesis of novel 4(3H)-quinazolinonyl aminopyrimidine derivatives has been achieved via quinazolinonyl enones which in turn were obtained from 2-acyl-4(3H)-quinazolinone. They have been assayed for biofilm inhibition against Gram-positive (methicillin-resistant Staphylococcus aureus (MRSA)) and Gram-negative bacteria (Acinetobacter baumannii). The analogues with 2,4,6-trimethoxy phenyl, 4-methylthio phenyl, and 3-bromo phenyl substituents (5h, 5j & 5k) have been shown to inhibit biofilm formation efficiently in MRSA with IC50 values of 20.7-22.4 mu M). The analogues 5h and 5j have demonstrated low toxicity in human cells in vitro and can be investigated further as leads.
About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Rasapalli, S; Murphy, ZF; Sammeta, VR; Golen, JA; Weig, AW; Melander, RJ; Melander, C; Macha, P; Vasudev, MC or concate me.. Name: 2,5-Dimethoxybenzaldehyde
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com