I found the field of Chemistry very interesting. Saw the article Ir-III-Catalyzed Selectiveortho-Monoiodination of Benzoic Acids with Unbiased C-H Bonds published in 2020. SDS of cas: 99-04-7, Reprint Addresses Martin-Matute, B (corresponding author), Stockholm Univ, Dept Organ Chem, S-10691 Stockholm, Sweden.; Johansson, MJ (corresponding author), AstraZeneca, Med Chem Res & Early Dev, Cardiovasc Renal & Metab CVRM, BioPharmaceut R&D, Gothenburg, Sweden.. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid
An iridium-catalyzed selectiveortho-monoiodination of benzoic acids with two equivalent C-H bonds is presented. A wide range of electron-rich and electron-poor substrates undergo the reaction under mild conditions, with >20:1 mono/di selectivity. Importantly, the C-H iodination occurs selectivelyorthoto the carboxylic acid moiety in substrates bearing competing coordinating directing groups. The reaction is performed at room temperature and no inert atmosphere or exclusion of moisture is required. Mechanistic investigations revealed a substrate-dependent reversible C-H activation/protodemetalation step, a substrate-dependent turnover-limiting step, and the crucial role of the Ag(I)additive in the deactivation of the iodination product towards further reaction.
SDS of cas: 99-04-7. Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com