I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Development of Fluorescently Labeled SSEA-3, SSEA-4, and Globo-H Glycosphingolipids for Elucidating Molecular Interactions in the Cell Membrane published in 2019. Name: Benzoic anhydride, Reprint Addresses Suzuki, KGN; Ando, H (corresponding author), Gifu Univ, United Grad Sch Agr Sci, 1-1 Yanagido, Gifu 5011193, Japan.; Suzuki, KGN; Ando, H (corresponding author), Gifu Univ, Ctr Highly Adv Integrat Nano & Life Sci G CHAIN, 1-1 Yanagido, Gifu 5011193, Japan.. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride
Glycosphingolipids (GSLs), such as the globo-series GSLs stage-specific embryonic antigen 3 (SSEA-3), SSEA-4, and Globo-H, are specifically expressed on pluripotent stem cells and cancer cells, and are known to be associated with various biological processes such as cell recognition, cell adhesion, and signal transduction. However, the behavior and biological roles of these GSLs are still unclear. In our previous study, we observed the interactions between the lipid raft and GSLs in real-time using single-molecule imaging, where we successfully synthesized various fluorescent analogs of GSLs (e.g., GM1 and GM3). Here, we have developed fluorescent analogs of SSEA-3, SSEA-4, and Globo-H using chemical synthesis. The biophysical properties of these analogs as raft markers were examined by partitioning giant plasma membrane vesicles from RBL-2H3 cells into detergent-resistant membrane fractions and liquid-ordered/liquid-disordered phases. The results indicated that the analogs were equivalent to native-type GSLs. The analogs could be used to observe the behavior of globo-series GSLs for detailing the structure and biological roles of lipid rafts and GSL-enriched nanodomains during cell differentiation and cell malignancy.
Welcome to talk about 93-97-0, If you have any questions, you can contact Asano, S; Pal, R; Tanaka, HN; Imamura, A; Ishida, H; Suzuki, KGN; Ando, H or send Email.. Name: Benzoic anhydride
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com