In 2019 ANGEW CHEM INT EDIT published article about ASYMMETRIC HYDROGENATION; PRACTICAL SYNTHESIS; KINETIC RESOLUTION; PHOSPHORUS LIGANDS; AMINO-ACIDS; MECHANISM; OLEFINS; COMPLEXES; TOFACITINIB; SCOPE in [Li, Chengxi; Wan, Feng; Chen, Yuan; Peng, Henian; Tang, Wenjun] Univ Chinese Acad Sci, Shanghai Inst Organ Chem, Ctr Excellence Mol Synth, State Key Lab Bioorgan & Nat Prod Chem, 345 Ling Ling Rd, Shanghai 200032, Peoples R China; [Yu, Shu; McWilliams, J. Christopher; Mustakis, Jason; Samp, Lacey] Pfizer Global R&D, Chem Res & Dev, Eastern Point Rd, Groton, CT 06340 USA; [Maguire, Robert J.] Pfizer Global R&D, Chem Res & Appl Synthet Technol, Eastern Point Rd, Groton, CT 06340 USA in 2019, Cited 90. The Name is Benzoic anhydride. Through research, I have a further understanding and discovery of 93-97-0. Formula: C14H10O3
We herein report the development of a conformationally defined, electron-rich, C-2-symmetric, P-chiral bisphosphorus ligand, ArcPhos, by taking advantage of stereoelectronic effects in ligand design. With the Rh-ArcPhos catalyst, excellent enantioselectivities and unprecedentedly high turnovers (TON up to 10 000) were achieved in the asymmetric hydrogenation of aliphatic carbocyclic and heterocyclic tetrasubstituted enamides, to generate a series of chiral cis-2-alkyl-substituted carbocyclic and heterocyclic amine derivatives in excellent enantiomeric ratios. This method also enabled an efficient and practical synthesis of the Janus kinase inhibitor (R)-tofacitinib.
Formula: C14H10O3. About Benzoic anhydride, If you have any questions, you can contact Li, CX; Wan, F; Chen, Y; Peng, HN; Tang, WJ; Yu, S; McWilliams, JC; Mustakis, J; Samp, L; Maguire, RJ or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com