Category: isothiazole. I found the field of Chemistry very interesting. Saw the article N-Benzoyl-protected Peptide Nucleic Acid (PNA) Monomers Expand the Range of Nucleobases Available for PNA-DNA Chimera published in 2019, Reprint Addresses Wada, T (corresponding author), Tohoku Univ, IMRAM, Aoba Ku, 2-1-1 Katahira, Sendai, Miyagi 9808577, Japan.. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride.
We synthesized N-benzoyl-protected peptide nucleic acid (PNA) monomers, which are robust under the conditions for deprotecting the 9-fluorenylmethoxycarbonyl (Fmoc) group by piperidine but are removable by aqueous ammonia and hence totally compatible with Fmoc-solid phase synthesis. This new invention expands the range of available nucleobase sequences, allowing us to use acid-sensitive PNA oligomers and purine nucleotides (both of which are difficult to use in the conventional methods) in the preparation of PNA-DNA chimeras to avoid the drawbacks of traditional PNAs.
About Benzoic anhydride, If you have any questions, you can contact Inagaki, M; Uematsu, R; Mizutani, T; Unabara, D; Araki, Y; Sakamoto, S; Kashida, H; Nishijima, M; Asanuma, H; Inoue, Y; Wada, T or concate me.. Category: isothiazole
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com