Recently I am researching about OXIDATIVE-ADDITION; ALKYL BROMIDES; TERTIARY ALKYL; NI; FUNCTIONALIZATION; HALIDES; REMOTE; CARBOXYLATION; ELECTROPHILES; SELECTIVITY, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21702151, 21871211, 21822303, 21703159]; Fundamental Research Funds for Central UniversitiesFundamental Research Funds for the Central Universities [2042019kf0208, 2018CDXZ0002, 2018CDPTCG0001/4]. Published in NATURE PUBLISHING GROUP in LONDON ,Authors: Li, YQ; Luo, YX; Peng, L; Li, YY; Zhao, BZ; Wang, W; Pang, HL; Deng, Y; Bai, RP; Lan, Y; Yin, GY. The CAS is 151-10-0. Through research, I have a further understanding and discovery of 1,3-Dimethoxybenzene. Category: isothiazole
Cross-coupling reactions have developed into powerful approaches for carbon-carbon bond formation. In this work, a Ni-catalyzed migratory Suzuki-Miyaura cross-coupling featuring high benzylic or allylic selectivity has been developed. With this method, unactivated alkyl electrophiles and aryl or vinyl boronic acids can be efficiently transferred to diarylalkane or allylbenzene derivatives under mild conditions. Importantly, unactivated alkyl chlorides can also be successfully used as the coupling partners. To demonstrate the applicability of this method, we showcase that this strategy can serve as a platform for the synthesis of terminal, partially deuterium-labeled molecules from readily accessible starting materials. Experimental studies suggest that migratory cross-coupling products are generated from Ni(0/II) catalytic cycle. Theoretical calculations indicate that the chain-walking occurs at a neutral nickel complex rather than a cationic one. In addition, the original-site cross-coupling products can be obtained by alternating the ligand, wherein the formation of the products has been rationalized by a radical chain process.
About 1,3-Dimethoxybenzene, If you have any questions, you can contact Li, YQ; Luo, YX; Peng, L; Li, YY; Zhao, BZ; Wang, W; Pang, HL; Deng, Y; Bai, RP; Lan, Y; Yin, GY or concate me.. Category: isothiazole
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com