An article NH4OAc-Promoted Domino Route to Hydroxyarylated Unsymmetrical Pyridines under Neat Conditions WOS:000516665800033 published article about CYCLIC SULFAMIDATE IMINES; HIGHLY SUBSTITUTED PYRIDINES; N-SULFONYL KETIMINES; BAYLIS-HILLMAN ACETATES; ONE-POT SYNTHESIS; MODULAR SYNTHESIS; TOPOISOMERASE-I; HYDROXYLATION; CYCLOADDITION; CONDENSATION in [Prakash, Meher; Gudimella, Santosh K.; Lodhi, Rajni; Guiri, Soumitra; Samanta, Sampak] Indian Inst Technol Indore, Discipline Chem, Indore 453552, Madhya Pradesh, India in 2020.0, Cited 81.0. Formula: C9H10O3. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7
A new metal-, oxidant-, and solvent-free ecofriendly domino method has been established for modular synthesis of a diverse range of medicinally promising hydroxyarylated unsymmetrical pyridines in good to high chemical yields with an excellent regioselectivity. This domino process involves a range of N-sulfonyl ketimines as C,N-binucleophiles, enolizable ketones, and aromatic/heteroaromatic aldehydes using ammonium acetate as an ideal promoter under neat conditions, which creates two new C-C bonds and one C-N bond. Notably, the neutral reaction conditions are mild enough to tolerate a range of functionalities and cover a variety of substrates, thus bestowing a powerful avenue to access tri- and tetrasubstituted pyridines including carbo- and heterocyclic fused ones. Interestingly, a practical, scalable, and high-yielding synthesis of pyridylphenol derivatives was successfully accomplished by our unique method.
Formula: C9H10O3. About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Prakash, M; Gudimella, SK; Lodhi, R; Guiri, S; Samanta, S or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com