Wang, FF; Li, XY; Li, ZY; Zhou, SL; Zhang, W in [Wang, Feifan; Li, Xiaoyue; Li, Zhongyu; Zhou, Shuangliu; Zhang, Wu] Anhui Normal Univ, Coll Chem & Mat Sci, Wuhu 241000, Peoples R China; [Zhou, Shuangliu; Zhang, Wu] Anhui Normal Univ, Key Lab Funct Mol Solids, Minist Educ, Wuhu 241000, Peoples R China published Copper Salts/TBAB-Catalyzed Chemo- and Regioselective beta-C(sp(3))-H Acyloxylation of Aliphatic Amides in 2019, Cited 80. COA of Formula: C8H8O2. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.
An efficient Cu(II)-catalyzed and tetrabutylammonium bromide (TBAB)-promoted strategy for highly regioselective and chemoselective C(sp(3))-H acyloxylation of aliphatic amides is described. Acyloxylation occurs selectively at the beta position with a broad substrate scope of carboxylic acids and aliphatic amides and good functional group compatibility. Notably, the competing reaction of intramolecular dehydrogenative amidation and intermolecular acyloxylation could be efficiently controlled by the amount of copper salt and the addition of TBAB. The intramolecular dehydrogenative amidation product was obtained in high yield when the amount of copper salts was increased. However, when TBAB was used as an additive, a preference for acyloxylation over intramolecular amidation was observed and the acyloxylated products were obtained in good yield. Preliminary studies were carried out to gain insights into the mechanism.
COA of Formula: C8H8O2. About 3-Methylbenzoic acid, If you have any questions, you can contact Wang, FF; Li, XY; Li, ZY; Zhou, SL; Zhang, W or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com