Quality Control of 3-Methylbenzoic acid. Recently I am researching about CAGE B-H; O-CARBORANES; ORTHO-ARYLATION; BORON CLUSTERS; DRUG DISCOVERY; GAMMA-LACTAMS; BENZOIC-ACIDS; BONDS; RHODIUM; FUNCTIONALIZATION, Saw an article supported by the Research Grants Council of The Hong Kong Special Administration RegionHong Kong Research Grants Council [14305017, 14305018, 14305918]; Faculty of Science, CUHK. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Au, YK; Lyu, HR; Quan, YJ; Xie, ZW. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid
Ir-catalyzed cascade dehydrogenative CH/BH and BH/OH cross-coupling of carboranyl carboxylic acid with readily available benzoic acid has been achieved, leading to the facile synthesis of previously unavailable carborano-coumarin in a simple one-pot process. Two cage B-H, one aryl C-H and one O-H bonds are activated to construct efficiently new B-C and B-O bonds. The cascade cyclization can stop at the first B-H/C-H cross-coupling step by tuning the reaction conditions, resulting in a series of alpha-carboranyl benzoic acid and aryl carborane derivatives. Control experiments indicate that B-H/C-H dehydrocoupling proceeds preferentially over B-H/O-H dehydrocoupling, and both directing groups and oxidants are crucial for this reaction. An iridium(V) intermediate is proposed to be involved in the catalytic cycle.
Quality Control of 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Au, YK; Lyu, HR; Quan, YJ; Xie, ZW or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com