Computed Properties of C8H10O2. I found the field of Chemistry very interesting. Saw the article The Natural Product Elegaphenone Potentiates Antibiotic Effects against Pseudomonas aeruginosa published in 2019, Reprint Addresses Sieber, SA (corresponding author), Tech Univ Munich, CIPS, Dept Chem, Lichtenbergstr 4, D-85747 Garching, Germany.. The CAS is 151-10-0. Through research, I have a further understanding and discovery of 1,3-Dimethoxybenzene.
Natural products represent a rich source of antibiotics that address versatile cellular targets. The deconvolution of their targets via chemical proteomics is often challenged by the introduction of large photocrosslinkers. Here we applied elegaphenone, a largely uncharacterized natural product antibiotic bearing a native benzophenone core scaffold, for affinity-based protein profiling (AfBPP) in Gram-positive and Gram-negative bacteria. This study utilizes the alkynylated natural product scaffold as a probe to uncover intriguing biological interactions with the transcriptional regulator AlgP. Furthermore, proteome profiling of a Pseudomonas aeruginosa AlgP transposon mutant provided unique insights into the mode of action. Elegaphenone enhanced the elimination of intracellular P.aeruginosa in macrophages exposed to sub-inhibitory concentrations of the fluoroquinolone antibiotic norfloxacin.
About 1,3-Dimethoxybenzene, If you have any questions, you can contact Zhao, WN; Cross, AR; Crowe-McAuliffe, C; Weigert-Munoz, A; Csatary, EE; Solinski, AE; Krysiak, J; Goldberg, JB; Wilson, DN; Medina, E; Wuest, WM; Sieber, SA or concate me.. Computed Properties of C8H10O2
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com