I found the field of Chemistry very interesting. Saw the article Palladium-Catalyzed Enantioselective Heteroarenyne Cycloisomerization Reaction published in 2021. Name: Benzoic anhydride, Reprint Addresses Jia, YX (corresponding author), Zhejiang Univ Technol, Coll Chem Engn, State Key Lab Breeding Base Green Chem Synth Tech, Chaowang Rd 18, Hangzhou 310014, Peoples R China.; Jia, YX (corresponding author), Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China.. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride
The extensively developed ene-type enantioselective cycloisomerization of classical 1,n-enynes provides an efficient approach to chiral cyclic 1,4-dienes. In contrast, the catalytic asymmetric heteroarenyne (heteroarene-alkyne) cycloisomerization involving the dearomative transformation of endocyclic aromatic C=C bonds remains unknown. Herein, we communicate a PdH-catalyzed enantioselective heteroarenyne cycloisomerization reaction of alkyne-tethered indole substrates (formal 1,5- and 1,6-enynes). Based on this strategy, a variety of structurally diverse chiral spiro and fused indoline derivatives bearing quaternary stereocenters and exocyclic C=C bonds are afforded in moderate to excellent yields and excellent enantioselectivities (up to 98 % ee). The classical ene-type enantioselective 1,5-enyne cycloisomerization of N-vinylpropiolamides is also developed to afford chiral 2-pyrrolones in good to excellent ee values.
Name: Benzoic anhydride. About Benzoic anhydride, If you have any questions, you can contact Liang, RX; Song, LJ; Lu, JB; Xu, WY; Ding, C; Jia, YX or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com